An Explainable Hybrid Deep Learning Framework for Knee Deterioration Level Prediction and Surgery Recommendation


Date Published : 10 September 2026

Contributors

kalpana Nagpal

Amity Institute of Pharmacy, Amity University, India
Author

Manimegalai P

Post Doctoral Researcher ,lincoln University College ,Malaysia
Author

Keywords

Knee Osteoarthritis Surgery Prediction Explainable Artificial Intelligence Clinical Decision Support System Machine Learning

Proceeding

Track

General Track

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Copyright (c) 2026 Sustainable Global Societies Initiative

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Abstract

Osteoarthritis is a degenerative joint disease which primarily affects the knee and has a major effect on quality of life and mobility. The Kellgren-Lawrence (KL) grading system used in conventional diagnosis depends on the subjective and human error-prone manual interpretation of X-rays. To overcome this limitation, this study offers a multimodal, explainable framework that combines radiographic imaging and clinical information to automatically assess knee osteoarthritis using the Kellgren–Lawrence scale and suggest surgery when necessary. The clinical segment achieves 93.3% accuracy using a stacked ensemble of XGBoost, LightGBM, and CatBoost trained on functional, symptomatic, and demographic data such as age, BMI, KOOS pain score, edema, and crepitus. The imaging segment achieves 80% accuracy by fine-tuning EfficientNetV2L with a Transformer head on 5,000  knee X-rays. Decision-level weighted fusion of both  produces a hybrid system with 94% accuracy on a test set of 900 samples. Explainability is provided through SHAP for clinical feature  and LIME for image , allowing clinicians to examine both numerical and visual explanations for each prediction. The suggested framework gives a dependable, understandable, and clinically significant approach for OA severity classification and surgical recommendation, for real-time hospital implementation, longitudinal disease monitoring, multi-center validation, and integration of biomechanical parameters.

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How to Cite

Nagpal, kalpana, & P, M. (2026). An Explainable Hybrid Deep Learning Framework for Knee Deterioration Level Prediction and Surgery Recommendation. Sustainable Global Societies Initiative, 1(11). https://vectmag.com/sgsi/paper/view/1230